Cannizzaro Reaction

This redox disproportionation of non-enolizable aldehydes to carboxylic acids and alcohols is conducted in concentrated base.

α-Keto aldehydes give the product of an intramolecular disproportionation in excellent yields.

Mechanism of the Cannizzaro Reaction

An interesting variant, the Crossed Cannizzaro Reaction, uses formaldehyde as reducing agent:

At the present time, various oxidizing and reducing agents can be used to carry out such conversions (with higher yields), so that today the Cannizzaro Reaction has limited synthetic utility except for the abovementioned conversion of α-keto aldehydes.

The Cannizzaro Reaction should be kept in mind as a source of potential side products when aldehydes are treated under basic conditions.

source : http://www.organic-chemistry.org/namedreactions/cannizzaro-reaction.shtm

Share this article on:

Quick Reply

Reply

	Some HTML allowed.
	Keep your comments above the belt or risk having them deleted.
	Signup for a avatar to have your pictures show up by your comment
	If Members see a thread that violates the Posting Rules, bring it to the attention of the Moderator Team

Free Sign Up!

Cannizzaro Reaction

Mechanism of the Cannizzaro Reaction

Quick Reply

Reply

Preparing for IIT-JEE ?

Arihant Revision Package for IIT JEE - Books, Practice Tests + Rank Predictor

@ INR 1,995/-

For Quick Info