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29 Dec 2010 15:22:36 IST

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difference between renin and rennin?

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difference between renin and rennin?

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Jnandeep Sarma

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Joined: 2 Apr 2010

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31 Dec 2010 13:57:22 IST

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renin is an enzyme that controls body's renin-angiotensin system (RAS) that mediates extracellular volume (i.e., that of the blood plasma, lymph and interstitial fluid, it regulates the body's mean arterial blood pressure.whereas rennin is the enzyme that digest milk proteins...

Juhi Sharma

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30 Jan 2011 14:22:31 IST

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hi

Chymosin, also known as rennin, is produced by the chief cells found in the stomach. These chief cells secrete an inactivated enzyme or zymogen called pro-rennin. When pro-rennin is exposed to the highly acidic environment inside the stomach (1M HCl), it is cleaved into what we know as chymosin. Chymosin is a catabolic enzyme that is in charge of the catalytic conversion of the protein milk caseinogen into paracasein, which is precipitated in the stomach as a calcium salt . This precipitate forms a firm curd in the stomach of young mammals that ensures that the milk stays in the stomach so that it may become exposed to the actions of proteolytic enzymes and the highly acidic gastric juice

The renin-angitensin system (RAS) has long been considered an exception to the general endocrine systems in that the enzyme responsible for pro-hormone to hormone conversion is secreted from the source organ kidney into the blood. The effector peptide angiotensin II is produced extracellularly, thus facilitating its rapid transport to the classical target organs such as the adrenal cortex. Here it affects the production of antidiuretic hormone (ADH) as well as constriction of the afferent arteriole and glomerular mesangium, which leads to a decrease in glomerular filtration and the endothelial cells of the vascular system !!!!!

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