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Botany

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8 May 2010 17:28:18 IST

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What radioactive marker is used for blood flow? P/Co/I/Na

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What radioactive marker is used for blood flow? P/Co/I/Na

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canorous

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8 May 2010 18:11:57 IST

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azalea

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8 May 2010 18:13:33 IST

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Really? Tell me more about it.

canorous

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8 May 2010 18:15:47 IST

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http://circ.ahajournals.org/cgi/content/full/118/16/1668

vignesh the cooler version of newton

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11 May 2010 18:25:29 IST

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i think d answer can never ever be Na or P.. coz both of them can easily cross the blood capillary barrier.. and if something can cross over from blood to interstitial fluid, dere is no point using it to determine the blood flow... because margin of errror wud be very high .. RISA = radiolabelled Iodine containing Serum Albumin is one thing used for this... so best answer is iodine.. and sahell, if u want any referance, medical physiology by Guyton ( a standard buk) is what i'm telling from... i hope PMT guyz accept medical buks as referance.. :D..

Sahell

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11 May 2010 19:47:48 IST

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Not sure if they'll accept it or not but don't need it for this 1... i thought the same thing bout Na and was thinking P may be used for bones and I for thyroid so guessed Co... thanks tho... where u at rite now?

canorous

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11 May 2010 19:58:31 IST

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i do totally agree with vignesh, he is a doctor afterall, .........but u know my answer ws not entirely baseless. Go chk on the link i supplied. The radioactive Na used for the purpose is in a complex and not free to be transferred accross living membranes

Sahell

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11 May 2010 20:09:27 IST

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didn't like the heat?

canorous

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11 May 2010 20:10:59 IST

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u'll be an adequate doctor. near accurate diagnosis.

Sahell

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11 May 2010 20:17:42 IST

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that's why the new account?

canorous

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11 May 2010 20:23:17 IST

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yes - didn't like being conspicuous on the top of the top members' list

Sahell

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11 May 2010 20:28:06 IST

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that's where the hats take you...how u preparing for finals?

canorous

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11 May 2010 20:29:56 IST

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please anything but that question ! :{

Sahell

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11 May 2010 20:34:54 IST

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why not?

canorous

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11 May 2010 20:36:26 IST

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don't u remember i had once answered that question. if u don't, i won't write that stuff agn n agn

vignesh the cooler version of newton

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14 May 2010 16:46:51 IST

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hey guyz cumon... all d best dears... do well... hope i see some of u here at MAMC.... and others in AIIMS....

edison

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19 Sep 2011 13:58:41 IST

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Three radioactive blood flow markers (RBFMs) are clinically available and in widespread use:

(1) thallium Tl 201 chloride,

(2) technetium Tc-99m sestamibi (Cardiolite; Lantheus Medical Imaging, North Billerica, Mass), and

(3) technetium Tc-99m tetrofosmin (Myoview; GE Healthcare, Princeton, NJ). In the present review,

These agents will be referred to by their nonproprietary names. The oldest of the 3 RBFMs, thallium 201, has been in use since approximately 1980, and the original experimental and clinical validation studies of MPI were performed with this agent. More recently, 99mTc-labeled sestamibi, approved in 1990, and tetrofosmin, approved in 1995, have been developed and validated clinically.

In comparative imaging studies analyzed for accuracy (sensitivity, specificity, and normalcy rates), no obvious differences have been found among these 3 agents. Each RBFM has unique properties that determine the logistics of its use and its test performance characteristics. The purpose of the present review is to compare and contrast these 3 RBFMs. It is hoped this detailed overview will assist clinicians in choosing which agent(s) to use and in understanding how each specific RBFM contributes to the results of an imaging study.

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