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SN2 Mechanism Overview: The general form of the SN2 mechanism is as follows:nuc: = nucleophileX = leaving group (usually halide or tosylate) The SN2 reaction involves displacement of a leaving group (usually a halide or a tosylate), by a nucleophile. This reaction works the best with methyl and primary halides because bulky alkyl groups block the backside attack of the nucleophile, but the reaction does work with secondary halides (although it is usually accompanied by elimination), and will not react at all with tertiary halides. In the following example, the hydroxide ion is acting as the nucleophile and bromine is the leaving group: Because o
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submitted by aankurverma (1310 m) on 22 Jul 2007 19:14:49 IST (12 comments 457 views)
