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NUCLEOPHILIC SUBSTITUTION REACTIONS: . All the nucleophilic substitution reactions begins with a Heterolytic cleavage of the bond between the sp 3 carbon and the leaving group. . This bond cleavage makes the sp3 carbon electron-deficient. . With the leaving group and a pair of electrons gone, the substrate is now a positively charged carbocation . . The nucleophile then reacts with this carbocation in a heterogenic bond forming the product. Most of the Aliphatic nucleophilic substitution reactions follow one of two mechanisms
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submitted by srujana (3100 m) on 14 Dec 2007 14:01:30 IST (30 comments 624 views)
